Image-derived input functions for PET brain studies
نویسندگان
چکیده
منابع مشابه
Spillover and partial-volume correction for image-derived input functions for small-animal 18F-FDG PET studies.
UNLABELLED We present and validate a method to obtain an input function from dynamic image data and 0 or 1 blood sample for small-animal 18F-FDG PET studies. The method accounts for spillover and partial-volume effects via a physiologic model to yield a model-corrected input function (MCIF). METHODS Image-derived input functions (IDIFs) from heart ventricles and myocardial time-activity curve...
متن کاملImage derived input function applied in CBF Studies with [15O]water PET in an integrated MR-PET
Institute of Neuroscience and Medicine, Forschungszentrum Jülich, Jülich, Germany To quantify CBF studies using [O]water PET an input function must be provided, e.g. by means of arterial blood sampling. An image derived input function (IDIF) gained from the dynamic PET images may be a non-invasive alternative. The time-activity curve (TAC) of the blood can be obtained from a volume of interest ...
متن کاملCalibrated image-derived input functions for the determination of the metabolic uptake rate of glucose with [18F]-FDG PET
PURPOSE We investigated the use of a simple calibration method to remove bias in previously proposed approaches to image-derived input functions (IDIFs) when used to calculate the metabolic uptake rate of glucose (K(m)) from dynamic [(18)F]-FDG PET scans of the thigh. Our objective was to obtain nonbiased, low-variance K(m) values without blood sampling. MATERIALS AND METHODS We evaluated eig...
متن کاملImage-derived input function from the vena cava for 18F-FDG PET studies in rats and mice.
UNLABELLED Measurement of arterial input function is a restrictive aspect for quantitative (18)F-FDG PET studies in rodents because of their small total blood volume and the related difficulties in withdrawing blood. METHODS In the present study, we took advantage of the high spatial resolution of a recent dedicated small-animal scanner to extract the input function from the (18)F-FDG PET ima...
متن کاملImage-Derived Input Function for Human Brain Using High Resolution PET Imaging with [11C](R)-rolipram and [11C]PBR28
BACKGROUND The aim of this study was to test seven previously published image-input methods in state-of-the-art high resolution PET brain images. Images were obtained with a High Resolution Research Tomograph plus a resolution-recovery reconstruction algorithm using two different radioligands with different radiometabolite fractions. Three of the methods required arterial blood samples to scale...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Journal of Nuclear Medicine and Molecular Imaging
سال: 2008
ISSN: 1619-7070,1619-7089
DOI: 10.1007/s00259-008-0986-8